Ismail Haniyeh will arrive for meetings with Foreign Minister Hossein Amir-Abdollahian and other senior Iranian officials.
Political analysts believe the visit is of great importance as it takes place just one day after the ceasefire resolution was adopted.
It is the second visit of the head of the political bureau of Hamas to Iran since the outbreak of the Israeli war on Gaza in October.
Haniyeh, who is based in the Qatari capital of Doha, met Leader of the Islamic Revolution Ayatollah Seyyed Ali Khamenei in November.
Iran is a key supporter of Hamas although it has repeatedly declared that groups operating within the Axis of Resistance, including Hamas, act independently when it comes to policy-making and military performance.
Resistant groups in Iraq, Lebanon, and Yemen have been supporting Hamas in its ongoing fight against the Israeli regime by launching attacks on Israeli interests or by targeting US military forces in the region.
Israel unleashed its war on Gaza on October 7 after Hamas carried out Operation Al-Aqsa Storm in retaliation for its intensified atrocities against the Palestinian people.
Since the start of the offensive, the Tel Aviv regime has killed more than 32,300 Palestinians and injured over 74,000 others.
Press TV